Testing of Glass Containers
These tests stated below are executed for the glass containers as per the United States Pharmacopoeia (USP) specification:
Powdered Glass Test for Glass Container
- The glass containers are gathered, cleaned, dried, crushed, sieved, and then once again crushed and sieved through a nest of sieves.
- The material that is still on the sieve is moved to a covered container and kept in desiccators.
- The sample is cleaned of iron particles, followed by an acetone wash, before being dried.
- Then, distilled water is added to 10 g of this sample of crushed glass in a conical flask before being autoclaved in Autoclave at 121°C for 30 minutes.
- After that, water is decanted (Transferred) into a different container, and the specimen’s washings made with distilled water are added to the leftover powdered glass.
- Using methyl red as the indicator, 0.02 N sulfuric acid is subsequently used to titrate the combined sample.
Water Attack Test for Glass Container
- Water Attack Test is performed for whole containers. The container is full with distilled water up to 90% of its capacity and is exposed to similar autoclaving conditions (121°C for 30 minutes) as that of powdered glass test.
- Within 60 minutes after autoclaving, the contents of the sample are collected and it is titrated against 0.02 N sulfuric acid in warm situations using methyl red as the indicator.
- The same approach is used for blank titration, but without the autoclaving step. The actual volume eaten (sample minus blank) shouldn’t be greater than the figure given below for the particular glass.
Glass Types and Their Test Limits
